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Summer E. Johansson, PhD 1 ; John T. Silk, PhD 1 ; Gregory L. Dugan, PhD 1 View author affiliations. Modeling data indicate that B. The increased transmissibility of the B. Higher vaccination coverage might need to be achieved to protect the public.
As of January 13,approximately 76 cases of B. The modeled trajectory of this variant in the U. Increased SARS-CoV-2 transmission might threaten strained health care resources, require extended and more rigorous implementation of public health strategies 4and increase the percentage united states free online dating population immunity required for pandemic control. Taking measures to reduce transmission now can lessen the potential impact of B. Collectively, enhanced genomic surveillance combined with continued compliance with effective public health measures, including vaccination, physical distancing, use of masks, hand hygiene, and isolation and quarantine, will be essential to limiting the spread of SARS-CoV-2, the virus that causes coronavirus disease COVID Strategic testing of persons without symptoms but at higher risk of infection, such as those exposed to SARS-CoV-2 or who have frequent unavoidable contact with the public, provides another opportunity to limit ongoing spread.
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Global genomic surveillance and rapid open-source sharing of viral genome sequences have facilitated near real-time detection, comparison, and tracking of evolving SARS-CoV-2 variants that can inform public health efforts to control the pandemic. Whereas some mutations in the viral genome emerge and then recede, others might confer a selective advantage to the variant, including enhanced transmissibility, so that such a variant can rapidly dominate other circulating variants.
Early in the pandemic, variants of SARS-CoV-2 containing the DG mutation in the spike S protein that increases receptor binding avidity rapidly became dominant in many geographic regions 56. In addition to the B. This report focuses on the emergence of the B. As of January 12,neither the B. The B. This variant has 13 other B. Multiple lines of evidence indicate that B. Variant B. To illustrate this effect, a simple, two-variant compartmental model was developed. The current U. For the model, initial assumptions included a B. These assumptions do not precisely represent any single U. The change in R t over time resulting from acquired immunity and increasing prevalence of B. Specifically, immunity against infection with either current variants or the B. In this model, B. With vaccination that protects against infection, the early epidemic trajectories do not change and B.
However, after B. Early efforts that can limit the spread of the B. Currently, there is no known difference in united states free online dating outcomes associated with the described SARS-CoV-2 variants; however, a higher rate of transmission will lead to more cases, increasing the number united states free online dating persons overall who need clinical care, exacerbating the burden on an already strained health care system, and resulting in more deaths. Continued genomic surveillance to identify B. The experience in the United Kingdom and the B. The increased transmissibility of this variant requires an even more rigorous combined implementation of vaccination and mitigation measures e. These measures will be more effective if they are instituted visit web page rather than later to slow the initial spread of the B.]
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