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The stock market crash marked the beginning of a decade of high unemployment , poverty, low profits, deflation , plunging farm incomes, and lost opportunities for economic growth as well as for personal advancement. Altogether, there was a general loss of confidence in the economic future. The usual explanations include numerous factors, especially high consumer debt, ill-regulated markets that permitted overoptimistic loans by banks and investors, and the lack of high-growth new industries. These all interacted to create a downward economic spiral of reduced spending, falling confidence and lowered production. Also hard hit was the manufacturing of durable goods like automobiles and appliances, whose purchase consumers could postpone. The economy hit bottom in the winter of —33; then came four years of growth until the recession of —38 brought back high levels of unemployment. dating a guy with depressionBelieve in yourself
Robert L. N Engl J Med Mar The two-step approach best balances burdens and benefits. James A. Pediatrics Mar 1.

Suicidality was more prevalent among students with current versus past prescription opioid misuse and with past versus no use. J Antimicrob Chemother Feb 1. Yet another study demonstrates increased acute kidney injury from vancomycin plus piperacillin compared with either drug alone.

Mary E. Lancet Feb 27 Chanda E. Lancet Feb 27 Bath D et al. Lancet Feb Trials in Africa showed that lethal lures plus screens were effective for integrated vector control and targeted indoor residual spraying was noninferior to mass indoor residual spraying. JAMA Feb Michael E. N Engl J Med Feb Most patients with heavily pretreated myeloma responded to idecabtagene vicleucel. Thomas L. The U. Allan S. Brett, MD reviewing Davies M et al.

Lancet Mar 2. An investigational 2. Kirsten E. J Am Coll Cardiol Jan Measurable clinical improvements in functional capacity and quality of life were seen after 6 months of treatment.]
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